Protective Effects of Artemisia persica Essential Oil Against Pentylenetetrazol-Induced Seizure in Male Mice with Emphasizing its Mechanism of Action

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Effects of Pretreatment with Satureja Bachtiarica Essential Oil in Preventing Seizure in Pentylenetetrazol-Kindled Mice

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BACKGROUND There have been some reports about the possible N-methyl-D-aspartate (NMDA) antagonist activity of Guaifenesin. As drugs with a similar structure to Guaifenesin (i.e. Felbamate) and those with NMDA antagonist activity have been clinically used as anticonvulsants, the aim of this study was to determine whether Guaifenesin has an anticonvulsant effect in an animal model of seizure. M...

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anticonvulsant effect of guaifenesin against pentylenetetrazol-induced seizure in mice

background: there have been some reports about the possible n-methyl-d-aspartate (nmda) antagonist activity of guaifenesin. as drugs with a similar structure to guaifenesin (i.e. felbamate) and those with nmda antagonist activity have been clinically used as anticonvulsants, the aim of this study was to determine whether guaifenesin has an anticonvulsant effect in an animal model of seizure. me...

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ژورنال

عنوان ژورنال: Iranian Red Crescent Medical Journal

سال: 2019

ISSN: 2074-1804,2074-1812

DOI: 10.5812/ircmj.85021